Thu,27 October 2011
Insulin-resistant men had significant improvement in erectile function when metformin was added to sildenafil (Viagra), according to data from a small clinical study.
Sildenafil alone had failed to improve erectile function, and men who received a placebo in addition to the phosphodiesterase-5 (PDE5) inhibitor continued to have erectile problems, Pablo Knoblovits, M.D., of Hospital Italiano de Buenos Aires in Argentina, reported here at the Endocrine Society meeting.
"We think metformin potentiates the activity of sildenafil by improving insulin resistance and nitric oxide a
|